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Volume · Design

XEOMIN

XEOMIN is Merz's botulinum toxin type A medication. It softens wrinkles by reducing recurrent expression-muscle contractions. Its manufacturing removes proteins surrounding the toxin, making it an option for those considering purification and repeat treatments.

Reviewed by the medical team · 2026.09.14

XEOMIN · manufacturer or supplier reference image

XEOMIN at a Glance

Treatment at a glance
ItemDetails
BrandXEOMIN
ManufacturerMerz
Ingredient classBotulinum toxin type A
Selection criteriaTreatment goals, muscle movement, previous products and responses
PlanConfirm dose and interval for the actual product and area

What is XEOMIN?

XEOMIN is Merz's botulinum toxin type A medication. It softens wrinkles by reducing recurrent expression-muscle contractions. Its manufacturing removes proteins surrounding the toxin, making it an option for those considering purification and repeat treatments.

Features emphasized by the manufacturer

Purification to remove complexing proteins

XEOMIN uses XTRACT purification to separate complexing proteins from botulinum toxin type A. This distinguishes and purifies the neurotoxin acting on muscle from surrounding proteins. Removing complexing proteins does not mean the product contains no protein or additives. (Purification technology)

Formulation considered for repeat treatment

The manufacturer highlights removal of complexing proteins as a key feature for repeat treatment. Regular patients may consider this alongside previous products, intervals and responses. XEOMIN does not eliminate resistance risk, so WayB also adjusts dose and intervals.

How does botulinum toxin work?

Botulinum toxin temporarily inhibits signals from nerves to muscles. We assess recurrent expression lines and muscle movement to determine treatment direction. WayB considers the properties of BOTOX, XEOMIN and HITOX alongside your previous responses.

We begin with the cause of your wrinkles.

We first assess whether expression lines predominate or muscle size or tension affects your contours. Wrinkles caused by sagging or hollowness have different causes, so we also assess whether volume or firming treatment is needed.

We check the product units and scope of use.

Equal numerical potency units across products do not mean equal amounts. We check the actual product information and treatment area, and do not determine dose or duration by brand name alone.

Can resistance develop?

The likelihood of botulinum toxin resistance varies with product, dose, intervals and treatment history. Using the medically appropriate dose and avoiding unnecessarily short intervals may help reduce the likelihood of neutralizing antibody formation.

Reduced effect does not always mean antibody-related resistance. We assess the previous product, dose, injection sites and muscle condition to plan the next treatment.

How are treatment and follow-up planned?

We review previous products, treatment dates, effects and uncomfortable reactions. We assess wrinkles and muscle movement to plan sites and doses, then check changes to determine the next treatment timing. Onset and duration vary by product and area.

Recovery & Precautions

Redness, swelling, bruising, tenderness or headache may occur. Effects on nearby muscles can cause temporary drooping eyelids, altered expressions, asymmetry or muscle weakness. Tell the clinic about unexpected movement or discomfort.

Seek emergency care immediately for difficulty breathing, swallowing or speaking, or severe generalized weakness. Before treatment, disclose pregnancy or breastfeeding, neuromuscular conditions, ingredient allergies and medications.

04 · QUESTIONS

Frequently Asked Questions

Can resistance develop to XEOMIN?

Although complexing proteins are removed, no guarantee can be made that resistance will never occur. Antibodies to botulinum toxin can form. Reduced effect may also relate to dose, injection site or muscle condition. Reviewing previous products, timing and responses is advisable.

Does it work equally on all wrinkles?

It is used to soften wrinkles related to expression-muscle movement. Wrinkles caused by sagging or deep creasing may not improve sufficiently by reducing muscle movement alone, so other treatments may be considered according to the cause.

Will switching products resolve resistance?

The cause of reduced effect must be assessed first. Along with product choice, we review dose, injection sites, intervals, muscle condition and previous responses to plan further treatment.

Can I directly compare unit counts between products?

Botulinum toxin potency units are determined by the product and assay method. We do not directly convert units between products; the medical team plans treatment for the actual product and area.

What history should I disclose before treatment?

Tell us about previous products and dates, effects and uncomfortable reactions. We also check neuromuscular conditions, allergies, medications, pregnancy and breastfeeding before treatment.

Which symptoms require immediate help after treatment?

Seek emergency care immediately for difficulty breathing, swallowing or speaking, or severe generalized weakness. Also tell the clinic about unexpected changes in expression or strength, or discomfort.

References

References for general treatment information. Please confirm your individual plan with the medical team.

It is okay to feel nervous about your first treatment.
You are welcome to visit even if you have not decided which treatment to choose.

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